Ageing 2007Meeting Program
 

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Friday September 28th  2007

18:00 Opening

Andreas Simm

Address
Rolf-Edgar Silber, Director of the Department of Cardiothoracic Surgery

Christoph Weiser, Vice Rector of the University

Steffen Hauptmann, Vice Dean of Research of the Medical Faculty
Thomas Klöss, Medical Director of the University Clinics
Eberhard Doege, Representative of the City Halle
Thomas Klie, President of the German Society of Gerontology and Geriatrics

Keynote lecture and Schober award

Laudation Thomas Rando by George Martin, Seattle, USA
Keynote lecture:
Thomas Rando, Stanford University, Palo Alto, USA
"Ageing of Tissue-Specific Stem Cells: The Role of the Systemic Environment"

20:00 Come Together


Saturday September 29th 2007

08:00 - 10:00 Session 1 - Mechanisms of ageing

Chair: Andreas Simm

Poly(ADP-ribosyl)ation and Cardiovascular Diseases: Good and Bad within DNA Repair Activity Sascha Beneke Konstanz, D
TERT and Endothelial cell aging Judith Haendeler Düsseldorf, D
Routes To Reversing Age Associated Thymic Atrophy Richard Aspinall London, UK
How the classical evolutionary biological theory of why we age elucidates the origins of human diseases of ageing George Martin Seattle, USA

10:00 – 10:30 Coffee Break

10:30 - 12:30 Session 2 - Protein modification during ageing

Chair: Jürgen Holtz

Degradation of oxidized proteins in aged microglial cells Tilman Grune Hohenheim, D
Protein maintenance in ageing: the role of oxidized protein repair Bertrand Friguet Paris, F
Advanced Glycation Endproducts and their receptor RAGE: markers of the biological age? Andreas Simm Halle, D
Human skin autofluorescence as a marker for advanced glycation endproduct accumulation during ageing Hugo Corstjens Oevel, B

12:30 - 13:30 Lunch Break

13:30 - 15:30 Session 3 - Oxidative Stress

Chair: George Martin

Oxidative-stress induced premature senescence of human diploid fibroblasts: comparison with replicative senescence Olivier Toussaint Namur, B
The potential role of premature senescence of structural cells in lung emphysema: evidence from experiments with parenchymal lung fibroblasts Olaf Holz Großhansdorf, D
Relationship between ageing-related stress and myocardial function in the Newcastle 85+ study Bernard Keavney Newcastle, UK
Oxidative stress in surgery and in heart failure: effects of ageing Franklin Rosenfeldt Melbourne, AUS

15:30 - 16:30 Poster Session / Coffee Break

16:30 - 19:00 Session 4 - Skeletal-Heart-Muscle connection

Chair: Franklin Rosenfeld

Age-related muscle weakness: strategies for reversal LaDora V. Thompson Minnesota, USA
Sarcopenia, from a clinical point of view Jürgen Bauer Nürnberg, D
Inflammation and Ageing Ursula Müller-Werdan Halle, D
Ageing, heart failure, and the skeletal muscle Stephan Gielen Leipzig, D
Bedrest after cardiac surgery: Big risks; little or no benefits Joseph Flaherty St. Louis, USA

20:00 Gala-Dinner (Moritzburg)


Sunday September 30th 2007

08:30 - 10:30 Session 5 - Regeneration of the myocardium

Chair: Tilman Grune

Age-related changes of endothelial progenitor cell function Robert Scheubel Halle, D
Regulation of the cardiomyocyte cell cycle Loren J. Field Indianapolis, USA
Clinical outcome of patients after stem cell treatment Christof Stamm Berlin, D
Progenitor cells: isolation, proliferation, and differentiation Christoph Piechaczek Bergisch Gladbach, D

10:30 - 11:30 Poster Session / Coffee Break

11:30 - 13:30 Session 6 - Prevention

Chair: Olivier Toussaint

Ageing intervention and prevention through mild stressed-induced hormesis in human cells Suresh Rattan Aarhus, DK
Modification of cardiometabolic pathways as a potentially new therapeutic approach for the ageing and the failing heart? Bernd Niemann Halle, D
Granzyme B inhibitors: A Novel Means of Preventing Age-Related Tissue Degeneration David Granville Vancouver, CAN
Healthy Ageing; form theory to implementation Jonathan Powell Bedford, UK

13:30 - 14:00 Farewell