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Friday September 28th 2007
18:00 Opening
Andreas Simm
Address
Rolf-Edgar Silber, Director of the Department of Cardiothoracic Surgery
Christoph Weiser, Vice Rector of the University
Steffen Hauptmann, Vice Dean of Research of the Medical Faculty
Thomas Klöss, Medical Director of the University Clinics
Eberhard Doege, Representative of the City Halle
Thomas Klie, President of the German Society of Gerontology and Geriatrics
Keynote lecture and Schober award
Laudation Thomas Rando by George Martin, Seattle, USA
Keynote lecture:
Thomas Rando,
Stanford University, Palo Alto, USA
"Ageing of Tissue-Specific Stem Cells: The Role of the Systemic Environment"
20:00 Come Together
Saturday September 29th 2007
08:00 - 10:00 Session 1 - Mechanisms of ageing
Chair: Andreas Simm
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Poly(ADP-ribosyl)ation and Cardiovascular Diseases: Good and Bad within
DNA Repair Activity |
Sascha Beneke |
Konstanz, D |
| TERT and Endothelial
cell aging |
Judith Haendeler |
Düsseldorf, D |
| Routes To
Reversing Age Associated Thymic Atrophy |
Richard Aspinall |
London, UK |
| How the
classical evolutionary biological theory of why we age elucidates the
origins of human diseases of ageing |
George Martin |
Seattle, USA |
10:00 – 10:30 Coffee Break
10:30 - 12:30 Session 2 - Protein modification during ageing
Chair: Jürgen Holtz
| Degradation
of oxidized proteins in aged microglial cells |
Tilman Grune |
Hohenheim, D |
| Protein
maintenance in ageing: the role of oxidized protein repair |
Bertrand Friguet |
Paris, F |
| Advanced
Glycation Endproducts and their receptor RAGE: markers of the biological
age? |
Andreas Simm |
Halle, D |
| Human skin
autofluorescence as a marker for advanced glycation endproduct
accumulation during ageing |
Hugo Corstjens |
Oevel, B |
12:30 - 13:30 Lunch Break
13:30
- 15:30 Session 3 - Oxidative Stress
Chair: George Martin
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Oxidative-stress induced premature senescence of human diploid
fibroblasts: comparison with replicative senescence |
Olivier Toussaint |
Namur, B |
| The potential
role of premature senescence of structural cells in lung emphysema:
evidence from experiments with parenchymal lung fibroblasts |
Olaf Holz |
Großhansdorf, D |
| Relationship
between ageing-related stress and myocardial function in the Newcastle
85+ study |
Bernard Keavney |
Newcastle, UK |
| Oxidative
stress in surgery and in heart failure: effects of ageing |
Franklin Rosenfeldt |
Melbourne, AUS |
15:30 - 16:30 Poster Session / Coffee Break
16:30 - 19:00 Session 4 - Skeletal-Heart-Muscle connection
Chair: Franklin Rosenfeld
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Age-related muscle weakness: strategies for reversal |
LaDora V. Thompson |
Minnesota, USA |
| Sarcopenia,
from a clinical point of view |
Jürgen Bauer |
Nürnberg, D |
|
Inflammation and Ageing |
Ursula
Müller-Werdan |
Halle, D |
| Ageing, heart
failure, and the skeletal muscle |
Stephan Gielen |
Leipzig, D |
| Bedrest after
cardiac surgery: Big risks; little or no benefits |
Joseph Flaherty |
St. Louis,
USA |
20:00 Gala-Dinner (Moritzburg)
Sunday
September 30th 2007
08:30 - 10:30 Session 5 - Regeneration of the myocardium
Chair: Tilman Grune
| Age-related
changes of endothelial progenitor cell function |
Robert Scheubel |
Halle, D |
| Regulation of
the cardiomyocyte cell cycle |
Loren J. Field |
Indianapolis, USA |
| Clinical
outcome of patients after stem cell treatment |
Christof Stamm |
Berlin, D |
| Progenitor
cells: isolation, proliferation, and differentiation |
Christoph Piechaczek |
Bergisch
Gladbach, D |
10:30 - 11:30 Poster Session / Coffee Break
11:30 - 13:30 Session 6 - Prevention
Chair: Olivier Toussaint
| Ageing
intervention and prevention through mild stressed-induced hormesis in
human cells |
Suresh Rattan |
Aarhus, DK |
| Modification
of cardiometabolic pathways as a potentially new therapeutic approach
for the ageing and the failing heart? |
Bernd Niemann |
Halle, D |
| Granzyme B
inhibitors: A Novel Means of Preventing Age-Related Tissue Degeneration |
David Granville |
Vancouver, CAN |
| Healthy
Ageing; form theory to implementation |
Jonathan Powell |
Bedford, UK |
13:30 - 14:00 Farewell
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