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DEPARTMENT OF PHARMACOLOGY
AND TOXICOLOGY
SECTION OF PHARMACOKINETICS
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DEPARTMENT OF PHARMACOLOGY
AND TOXICOLOGY
SECTION OF PHARMACOKINETICS
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Homepage: Section of Pharmacokinetics
List of abstracts since 1995:
1995
1. Weiss, M. and M.S. Roberts. Modelling the effect
of intra tissue diffusion on
distribution kinetics of drugs. Naunyn-Schmiedebergs
Arch. Pharmacol. 351:R48 (1995).
2. Looby, M., W. Sziegoleit, K. Pönicke,
and M. Weiss. Population pharmacokinetics
of trapidil (Rocornal) in diabetic
patients. Eur. J. Clin. Pharmacol. 49:A158
(1995).
3. Sziegoleit, W., M. Looby, M. Weiss, A. Hoffmann,
and B. Terhaag. Cardiovascular
effects of detajmium bitartrate in
healthy volunteers. Eur. J. Clin. Pharmacol.
49:A164
(1995).
1996
4. Weiss, M. Intrahepatische Mischung als
Grundlage der Modellierung der
hepatischen Pharmakokinetik. Klin. Pharmakol.
akt. 7:22-23 (1996).
5. Weiss, M. Physiological pharmacokinetics:
from organs to the whole body.
Eur. J. Clin. Pharmacol. 50:523 (1996).
6. Stedtler, C. and M. Weiss. Modellierung
der hepatischen Elimination - Einfluß
der Verteilungsdynamik. Klin. Pharmakol. akt.
7:23-24 (1996).
7. Looby, M. and M. Weiss. NONMEM - Analyse
der Dispositionskinetik von
Trapidil bei Patienten mit Leberzirrhose.
Klin. Pharmakol. akt. 7(1):28-29 (1996).
8. Wünscher, U., M. Looby, and M. Weiss.
Toxicokinetics of chlorodibromomethane
in rats after single oral dose.
Naunyn-Schmiedebergs Arch. Pharmacol. 353:R114 (1996).
9. Looby, M., R. Linke, and M. Weiss. Pharmacokinetics
of idarubicin and
idarubicinol in the rabbit. Naunyn-Schmiedebergs
Arch. Pharmacol. 353:R8 (1996).
1997
10. Weiss, M., W. Sziegoleit, M. Looby, B. Terhaag,
and A. Hoffmann. Pharmacokinetic-
pharmacodynamic (PKPD)
analysis of detajmium bitartrate after single intravenous dose
in healthy volunteers. Eur. J. Clin. Pharmacol.
52: A17 (1997).
11. Sziegoleit W, Weiss M, and Hübner G I.
Cardiovascular effects of orciprenaline during
continuous intravenous infusion
in healthy subjects. Eur. J. Clin. Pharmacol. 52: A 16 (1997).
1998
12. Ring, A., Tothfalusi, L., Endrenyi, L., and
Weiss, M. Performance of empirical
metrics of absorptionrate for extended
release dosage forms in bioequivalence studies.
Eur. J. Clin. Pharmacol. 54(6): A21 (1998).
13. Weiss, M., O.
Kuhlmann, G.-J. Krauss, and M. S. Roberts. Hepatocellular distribution
and elimination
kineticsof diclofenac in the isolated perfused rat liver. Naunyn-
Schmiedebergs Arch.
Pharmacol. 357:R6 (1998).
14. Sziegoleit W., Weiss M, and Hübner G
I. Cardiovascular effects of fenoterol during
continuous intravenous infusion
in healthy humans. Naunyn-Schmiedeberg’s Arch.
Pharmacol. 357: R 168 (1998).
1999
15. Kuhlmann, O., Roberts,
M.S., Weiss, M. Disposition of p-aminohippuric acid (PAH)
and kinetics of
themetabolite p-acetylaminohippuric acid (PAAH) in the in-situ perfused
rat liver. Naunyn-Schmiedebergs
Arch. Pharmacol. Suppl. to Vol. 359:R120 (1999).
16. Weiss, M. Modeling the anomalous pharmacokinetics
of amiodarone. Clin. Pharmacol.
Ther. 65: 180 (1999).
19. Weiss, M., Keiding, S., Schiott, K., Munk,
O., and Roelsgaard, K. Recirculatory
pharmacokinetic models of
pet radiotracers: Application to 13N-Ammonia.
Eur. J. Clin. Invest. Vol. 29, Suppl. 1:92, p.29
(1999).
20. Weiss, M., Sziegoleit, W., and G.I. Hübner.
Effects of hemodynamics in the
pharmacokinetics of sorbitol in healthy
volunteers: Recirculatory vs. compartmental
modeling. Eur. J. Pharm. Sci. Vol. 8: A149 (1999).
21. Lansky, P. and Weiss, M. Does the dose-solubility ratio affect the
mean distribution
time of drugs? Pharm. Res. 16: 1472-1478 (1999).
22. Bariszlovich, A., H.-G. Struck, M. Weiss, and O. Kuhlmann. 1999.
Zum Verlauf des
Kammerwasser- und Plasmaspiegels von Diclofenac bei intravenöser
Applikation vor
der Kataraktoperation. Abstract: Klin. Monatsbl. Augenheilk., 215(Suppl.
7):3.
2000
23. Kuhlmann, O., O. Jeschke, and M. Weiss. 2000. Effect
of bile acid on membrane permeation and
absorption kinetics
of diclofenac. Naunyn-Schmiedeberg's Arch. Pharmacol., 361(4):R122.
24. Bariszlovich, A., Struck, H.G., Weiss, M., and Kuhlmann, O. Zur
klinischen Wirksamkeit systemischer
Diclofenac-Gabe am Auge in Abhängigkeit von der Kammerwasserkonzentration.
(9. Jahrestagung der Gesellschaft der Augenärzte von Sachsen-Anhalt
und Thüringen, 14.-15.10.2000 in Suhl)
25. Struck, H.G., Bariszlovich, A., Kuhlmann, O., and Weiss, M. Diclofenac
level in aqueous humor and in plasma
after i.v.-injection. Ophthalmic Res. Sept. 2000, S. 140, 3333.
26. Kang, W., Kuhlmann, O., and Weiss, M. Effect of rutin on pharmacokinetics
and pharmacodynamics of
idarubicin in the isolated perfused rat heart. Eur. J. Pharm. Sci.
11(Suppl.1):S92, PO-188 (2000).
2001
27. Kuhlmann, O., Struck, H.G., Bariszlovich, A., and Weiss, M. Penetration
of iv administered diclofenac
into aqueous humor of patients undergoing cataract surgery. Arch. Pharma-col.
Suppl. to Vol. 363, Number 4, R121 (2001).
28. Weiss M., Kuhlmann O., and Struck H.G. Pharmacokinetic Modelling
of drug penetration to the eye.
Ophthalmic Res. Sept. 2001, S. 124, 2153.
29. Struck, H.G., Weller, C., and Weiss, M. Penetration and bioavailability
of topically applied steroids into the eye.
Ophthalmic Res. Sept. 2001, S. 125, 2155.
2002
30. Kang, W. and Weiss, M. Digoxin uptake, receptor interaction and
inotropic response in the isolated intact rat heart.
Naunyn-Schmiedeberg’s Arch Pharmacol. Vol. 365 (Suppl. 1) March 2002,
S. R92, 354.
Kuhlmann, O., Hofmann, S., Müller, S.P., and Weiss, M. Effect
of rutin and cinchonine on the pharmacokinetics of idarubicin
in the isolated perfused rat lung. Eur. J. Pharm. Sci. Vol. 17(1),
S66, 2002.
32. Voigt, W., Kegel, T., Weiss, M., Simon, H., Grothey, A., and Schmoll,
H.-J. Activity profiles of paclitaxel, gemcitabine,
vinorelbine and oxaliplatin in human anaplastic thyroid carcinoma cell
lines. Onkologie Sonderheft 4 zu Band 25, A908, 257, 2002.
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Last updated: February 21, 2003.